BDBM178000 US9120807, 12
SMILES: O=C(c1cccs1)c1nc(NCc2cccnc2)nc2cc(NCc3cccnc3)sc12
InChI Key: InChIKey=BXEPZMXZIXWQED-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM178000 (US9120807, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 256 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (A3) (Homo sapiens (Human)) | BDBM178000 (US9120807, 12) | GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 308 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2b (Homo sapiens (Human)) | BDBM178000 (US9120807, 12) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 68.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM178000 (US9120807, 12) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 828 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair |