BDBM178048 (3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclopent-1-en-1-yl]methanone (11)
SMILES: COc1ccc(cc1OC)C(=O)C1=C(CCC1)c1ccc(OC)c(OC)c1
InChI Key: InChIKey=BETABABWXFMMRK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM178048 ((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 228 | n/a | 599 | n/a | n/a | n/a | n/a | n/a | n/a |
Atat£rk University | Assay Description CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ... | Chem Biol Drug Des 87: 594-607 (2016) Article DOI: 10.1111/cbdd.12695 BindingDB Entry DOI: 10.7270/Q20R9N5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM178048 ((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 366 | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Atat£rk University | Assay Description CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ... | Chem Biol Drug Des 87: 594-607 (2016) Article DOI: 10.1111/cbdd.12695 BindingDB Entry DOI: 10.7270/Q20R9N5Q | |||||||||||
More data for this Ligand-Target Pair |