BDBM178082 3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (18)

SMILES: Nc1ncnc2[nH]nc(-c3ccc4ccccc4c3)c12

InChI Key: InChIKey=LQRSFPTVTRTRMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (Streptomyces chromofuscus)	BDBM178082 (3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-...) Show SMILES Nc1ncnc2[nH]nc(-c3ccc4ccccc4c3)c12 Show InChI InChI=1S/C15H11N5/c16-14-12-13(19-20-15(12)18-8-17-14)11-6-5-9-3-1-2-4-10(9)7-11/h1-8H,(H3,16,17,18,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	8.0	n/a
Roxbury Community College					Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...				Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V
					More data for this Ligand-Target Pair