BDBM178112 3-(4-fluorobenzyl)-5,6-dihydrospiro[benzo[d][1,2,3]triazole-4,2'-oxiran]-7(3H)-one (26)

SMILES: Fc1ccc(Cn2nnc3c2C2(CO2)CCC3=O)cc1

InChI Key: InChIKey=CXOPXFDRBKDYTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM178112 (3-(4-fluorobenzyl)-5,6-dihydrospiro[benzo[d][1,2,3...) Show SMILES Fc1ccc(Cn2nnc3c2C2(CO2)CCC3=O)cc1 Show InChI InChI=1S/C14H12FN3O2/c15-10-3-1-9(2-4-10)7-18-13-12(16-17-18)11(19)5-6-14(13)8-20-14/h1-4H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	7.5	n/a
German Cancer Research Center (DKFZ)					Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total...				ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR
					More data for this Ligand-Target Pair