BDBM178119 (2'R*,7R*)-3-benzyl-3,5,6,7-tetrahydrospiro [benzo[d][1,2,3]triazole-4,2'-oxiran]-7-yl benzoate (29a)

SMILES: O=C(O[C@@H]1CC[C@]2(CO2)c2c1nnn2Cc1ccccc1)c1ccccc1

InChI Key: InChIKey=SJGHBLZMRRMDNN-UTKZUKDTSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM178119 ((2'R*,7R*)-3-benzyl-3,5,6,7-tetrahydrospiro [b...) Show SMILES O=C(O[C@@H]1CC[C@]2(CO2)c2c1nnn2Cc1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C21H19N3O3/c25-20(16-9-5-2-6-10-16)27-17-11-12-21(14-26-21)19-18(17)22-23-24(19)13-15-7-3-1-4-8-15/h1-10,17H,11-14H2/t17-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
German Cancer Research Center (DKFZ)					Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total...				ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR
					More data for this Ligand-Target Pair