BDBM179317 US9126952, 20

SMILES: O=C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)N1CCCCC1

InChI Key: InChIKey=QRZJPGOUSPYSHN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179317 (US9126952, 20) Show SMILES O=C(C1CCCN(C1)c1ncnc2cc(ccc12)N1CCOCC1)N1CCCCC1 Show InChI InChI=1S/C23H31N5O2/c29-23(27-8-2-1-3-9-27)18-5-4-10-28(16-18)22-20-7-6-19(15-21(20)24-17-25-22)26-11-13-30-14-12-26/h6-7,15,17-18H,1-5,8-14,16H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair