null
SMILES: COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c(C)nnc3-c3ccccc3)c21
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 3 [326-398] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.40 | -10.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 [51-123] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 10 | -10.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [91-163] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 12 | -10.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [364-436] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 22 | -10.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [75-147] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 27 | -10.3 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [364-436] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 38 | -10.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [75-147] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 60 | n/a | n/a | n/a | 7.4 | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 [326-398] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 42 | n/a | n/a | n/a | 7.4 | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 [51-123] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 21 | n/a | n/a | n/a | 7.4 | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [364-436] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 36 | n/a | n/a | n/a | 7.4 | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [91-163] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 41 | n/a | n/a | n/a | 7.4 | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 [364-436] (Homo sapiens (Human)) | BDBM179474 (US9675697, Cpd. No. 25) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 36 | n/a | n/a | n/a | 7.4 | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin... | US Patent US9675697 (2017) BindingDB Entry DOI: 10.7270/Q2CC0XV6 | |||||||||||
More data for this Ligand-Target Pair |