BDBM179500 US9126976, 31

SMILES: O[C@H](CN1[C@@H](CN(Cc2cc(Cl)cc(Cl)c2)c2ccccc12)c1ccccc1)C(F)(F)F

InChI Key: InChIKey=KAFZDQIQQXFEMH-XZOQPEGZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM179500 (US9126976, 31) Show SMILES O[C@H](CN1[C@@H](CN(Cc2cc(Cl)cc(Cl)c2)c2ccccc12)c1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C24H21Cl2F3N2O/c25-18-10-16(11-19(26)12-18)13-30-14-22(17-6-2-1-3-7-17)31(15-23(32)24(27,28)29)21-9-5-4-8-20(21)30/h1-12,22-23,32H,13-15H2/t22-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...				US Patent US9126976 (2015) BindingDB Entry DOI: 10.7270/Q25B018M
					More data for this Ligand-Target Pair