BDBM179506 US9126976, 37

SMILES: O[C@H](CN1[C@@H](CN(CC2CCCCC2)c2ccccc12)c1cccc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=SATLPDVWOYYMGN-XZOQPEGZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM179506 (US9126976, 37) Show SMILES O[C@H](CN1[C@@H](CN(CC2CCCCC2)c2ccccc12)c1cccc(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C25H28F6N2O/c26-24(27,28)19-10-6-9-18(13-19)22-15-32(14-17-7-2-1-3-8-17)20-11-4-5-12-21(20)33(22)16-23(34)25(29,30)31/h4-6,9-13,17,22-23,34H,1-3,7-8,14-16H2/t22-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...				US Patent US9126976 (2015) BindingDB Entry DOI: 10.7270/Q25B018M
					More data for this Ligand-Target Pair