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SMILES: CC(C)Oc1cccc(CN2C[C@H](N(C[C@@H](O)C(F)(F)F)c3ccccc23)c2cccc(c2)C(F)(F)F)n1

InChI Key: InChIKey=CMIDTMYSJBUKPX-BJKOFHAPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179514   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM179514
PNG
(US9126976, 45)
Show SMILES CC(C)Oc1cccc(CN2C[C@H](N(C[C@@H](O)C(F)(F)F)c3ccccc23)c2cccc(c2)C(F)(F)F)n1 |r|
Show InChI InChI=1S/C27H27F6N3O2/c1-17(2)38-25-12-6-9-20(34-25)14-35-15-23(18-7-5-8-19(13-18)26(28,29)30)36(16-24(37)27(31,32)33)22-11-4-3-10-21(22)35/h3-13,17,23-24,37H,14-16H2,1-2H3/t23-,24+/m0/s1
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Similars
US Patent
n/an/a 750n/an/an/an/a7.425



Merck Sharp & Dohme Corp.

US Patent


Assay Description
First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...

US Patent US9126976 (2015)


BindingDB Entry DOI: 10.7270/Q25B018M
More data for this
Ligand-Target Pair