BDBM179517 US9126976, 48
SMILES: CCOc1cccc(CN2C[C@H](N(C[C@@H](O)C(F)(F)F)c3ccccc23)c2cccc(c2)C(F)(F)F)n1
InChI Key: InChIKey=OBUIPDVRRGUZPL-XZOQPEGZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM179517 (US9126976, 48) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 310 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo... | US Patent US9126976 (2015) BindingDB Entry DOI: 10.7270/Q25B018M | |||||||||||
More data for this Ligand-Target Pair |