null
SMILES: COc1cc2ccc(cc2cc1OC)[C@@H]1CN(Cc2cccc(OC(F)(F)F)c2)c2ccccc2N1C[C@@H](O)C(F)(F)F
InChI Key: InChIKey=PHCRRYJFGMWQCP-LITSAYRRSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM179519 (US9126976, 50) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 193 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo... | US Patent US9126976 (2015) BindingDB Entry DOI: 10.7270/Q25B018M | |||||||||||
More data for this Ligand-Target Pair |