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SMILES: O[C@H](CN1C(CN(C2C=Cc3ccccc23)c2ccccc12)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F

InChI Key: InChIKey=MTPIEDZICIYPQN-ZZVXHFGESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179525   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM179525
PNG
(US9126976, 56)
Show SMILES O[C@H](CN1C(CN(C2C=Cc3ccccc23)c2ccccc12)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F |r,c:8|
Show InChI InChI=1S/C28H23F7N2O2/c29-26(30)28(34,35)39-19-8-5-7-18(14-19)24-15-36(21-13-12-17-6-1-2-9-20(17)21)22-10-3-4-11-23(22)37(24)16-25(38)27(31,32)33/h1-14,21,24-26,38H,15-16H2/t21?,24?,25-/m1/s1
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MMDB

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UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/a7.425



Merck Sharp & Dohme Corp.

US Patent


Assay Description
First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...

US Patent US9126976 (2015)


BindingDB Entry DOI: 10.7270/Q25B018M
More data for this
Ligand-Target Pair