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SMILES: CC(C)(O)c1ccc(cc1)C1CN(Cc2cccc(OC(F)(F)F)c2)c2ccccc2N1C[C@@H](O)C(F)(F)F

InChI Key: InChIKey=LCGUAZUIXAARQF-WUBHUQEYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179528   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM179528
PNG
(US9126976, 59)
Show SMILES CC(C)(O)c1ccc(cc1)C1CN(Cc2cccc(OC(F)(F)F)c2)c2ccccc2N1C[C@@H](O)C(F)(F)F |r|
Show InChI InChI=1S/C28H28F6N2O3/c1-26(2,38)20-12-10-19(11-13-20)24-16-35(15-18-6-5-7-21(14-18)39-28(32,33)34)22-8-3-4-9-23(22)36(24)17-25(37)27(29,30)31/h3-14,24-25,37-38H,15-17H2,1-2H3/t24?,25-/m1/s1
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Similars
US Patent
n/an/a 24n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
An in vitro assay for determining ICso's to identify compounds that inhibit CETP transfer activity is performed based on a modification of a publishe...

US Patent US9126976 (2015)


BindingDB Entry DOI: 10.7270/Q25B018M
More data for this
Ligand-Target Pair