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SMILES: O[C@H](CN1C(CN(Cc2cccc(OC(F)(F)F)c2)c2ccccc12)c1cccc(OC(F)F)c1)C(F)(F)F

InChI Key: InChIKey=OJLDVIXFUWLYAU-OZAIVSQSSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179530   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM179530
PNG
(US9126976, 61)
Show SMILES O[C@H](CN1C(CN(Cc2cccc(OC(F)(F)F)c2)c2ccccc12)c1cccc(OC(F)F)c1)C(F)(F)F |r|
Show InChI InChI=1S/C26H22F8N2O3/c27-24(28)38-18-7-4-6-17(12-18)22-14-35(13-16-5-3-8-19(11-16)39-26(32,33)34)20-9-1-2-10-21(20)36(22)15-23(37)25(29,30)31/h1-12,22-24,37H,13-15H2/t22?,23-/m1/s1
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Similars
US Patent
n/an/a 7.5n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
An in vitro assay for determining ICso's to identify compounds that inhibit CETP transfer activity is performed based on a modification of a publishe...

US Patent US9126976 (2015)


BindingDB Entry DOI: 10.7270/Q25B018M
More data for this
Ligand-Target Pair