BindingDB logo
myBDB logout

null

SMILES: O[C@H](CN1[C@@H](CN(Cc2cccc(OC(F)F)c2)c2ccccc12)c1cccc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=PQFCNUNHVJKNCZ-XZOQPEGZSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179533   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM179533
PNG
(US9126976, 64)
Show SMILES O[C@H](CN1[C@@H](CN(Cc2cccc(OC(F)F)c2)c2ccccc12)c1cccc(c1)C(F)(F)F)C(F)(F)F |r|
Show InChI InChI=1S/C26H22F8N2O2/c27-24(28)38-19-8-3-5-16(11-19)13-35-14-22(17-6-4-7-18(12-17)25(29,30)31)36(15-23(37)26(32,33)34)21-10-2-1-9-20(21)35/h1-12,22-24,37H,13-15H2/t22-,23+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 16n/an/an/an/a7.425



Merck Sharp & Dohme Corp.

US Patent


Assay Description
First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...

US Patent US9126976 (2015)


BindingDB Entry DOI: 10.7270/Q25B018M
More data for this
Ligand-Target Pair