BDBM179536 US9126976, 67

SMILES: O[C@H](CN1[C@@H](CN(CC2CCOCC2)c2ccccc12)c1cccc(OC(F)(F)F)c1)C(F)(F)F

InChI Key: InChIKey=HPVKSEHFNOFYIK-FCHUYYIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM179536 (US9126976, 67) Show SMILES O[C@H](CN1[C@@H](CN(CC2CCOCC2)c2ccccc12)c1cccc(OC(F)(F)F)c1)C(F)(F)F |r| Show InChI InChI=1S/C24H26F6N2O3/c25-23(26,27)22(33)15-32-20-7-2-1-6-19(20)31(13-16-8-10-34-11-9-16)14-21(32)17-4-3-5-18(12-17)35-24(28,29)30/h1-7,12,16,21-22,33H,8-11,13-15H2/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...				US Patent US9126976 (2015) BindingDB Entry DOI: 10.7270/Q25B018M
					More data for this Ligand-Target Pair