null

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)C(C)=O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=PPANWYIFJPHSFO-PGYBXFQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179560 (US9126980, 5) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)C(C)=O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C38H45N5O5S/c1-5-7-19-41(20-8-6-2)38(47)35-21-26(3)43(39-35)36-18-15-31(40-49(48)33-16-13-28(14-17-33)27(4)45)23-34(36)37(46)42-24-30-12-10-9-11-29(30)22-32(42)25-44/h9-18,21,23,32,40,44H,5-8,19-20,22,24-25H2,1-4H3/t32-,49?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179560 (US9126980, 5) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)C(C)=O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C38H45N5O5S/c1-5-7-19-41(20-8-6-2)38(47)35-21-26(3)43(39-35)36-18-15-31(40-49(48)33-16-13-28(14-17-33)27(4)45)23-34(36)37(46)42-24-30-12-10-9-11-29(30)22-32(42)25-44/h9-18,21,23,32,40,44H,5-8,19-20,22,24-25H2,1-4H3/t32-,49?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	609	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair