BDBM179567 US9126980, 12

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(Oc3ccc(C)cc3)c2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=OKDLZEMFACLDAO-XYMJDGAWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179567 (US9126980, 12) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(Oc3ccc(C)cc3)c2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C43H49N5O5S/c1-5-7-22-46(23-8-6-2)43(51)40-24-31(4)48(44-40)41-21-18-34(26-39(41)42(50)47-28-33-13-10-9-12-32(33)25-35(47)29-49)45-54(52)38-15-11-14-37(27-38)53-36-19-16-30(3)17-20-36/h9-21,24,26-27,35,45,49H,5-8,22-23,25,28-29H2,1-4H3/t35-,54?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179567 (US9126980, 12) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(Oc3ccc(C)cc3)c2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C43H49N5O5S/c1-5-7-22-46(23-8-6-2)43(51)40-24-31(4)48(44-40)41-21-18-34(26-39(41)42(50)47-28-33-13-10-9-12-32(33)25-35(47)29-49)45-54(52)38-15-11-14-37(27-38)53-36-19-16-30(3)17-20-36/h9-21,24,26-27,35,45,49H,5-8,22-23,25,28-29H2,1-4H3/t35-,54?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair