BDBM179583 US9126980, 28
SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccccc2C(=O)OC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO
InChI Key: InChIKey=HGOQDWXCUZAHOY-ZKHQRSHRSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM179583 (US9126980, 28) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa... | US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM179583 (US9126980, 28) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 448 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa... | US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184 | |||||||||||
More data for this Ligand-Target Pair |