BDBM179586 US9126980, 31

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(Oc3ccc(F)cc3)cc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=HVWYQSTYYJOEKC-QYUVYRFSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179586 (US9126980, 31) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(Oc3ccc(F)cc3)cc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C42H46FN5O5S/c1-4-6-22-46(23-7-5-2)42(51)39-24-29(3)48(44-39)40-21-14-33(26-38(40)41(50)47-27-31-11-9-8-10-30(31)25-34(47)28-49)45-54(52)37-19-17-36(18-20-37)53-35-15-12-32(43)13-16-35/h8-21,24,26,34,45,49H,4-7,22-23,25,27-28H2,1-3H3/t34-,54?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179586 (US9126980, 31) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(Oc3ccc(F)cc3)cc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C42H46FN5O5S/c1-4-6-22-46(23-7-5-2)42(51)39-24-29(3)48(44-39)40-21-14-33(26-38(40)41(50)47-27-31-11-9-8-10-30(31)25-34(47)28-49)45-54(52)37-19-17-36(18-20-37)53-35-15-12-32(43)13-16-35/h8-21,24,26,34,45,49H,4-7,22-23,25,27-28H2,1-3H3/t34-,54?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair