BDBM179588 US9126980, 33

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(c2)-c2ccn(C)n2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=MMFDFLZMPZOOAN-UPHSDLEZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179588 (US9126980, 33) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(c2)-c2ccn(C)n2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C40H47N7O4S/c1-5-7-19-45(20-8-6-2)40(50)37-22-28(3)47(42-37)38-17-16-32(43-52(51)34-15-11-14-30(24-34)36-18-21-44(4)41-36)25-35(38)39(49)46-26-31-13-10-9-12-29(31)23-33(46)27-48/h9-18,21-22,24-25,33,43,48H,5-8,19-20,23,26-27H2,1-4H3/t33-,52?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179588 (US9126980, 33) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(c2)-c2ccn(C)n2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C40H47N7O4S/c1-5-7-19-45(20-8-6-2)40(50)37-22-28(3)47(42-37)38-17-16-32(43-52(51)34-15-11-14-30(24-34)36-18-21-44(4)41-36)25-35(38)39(49)46-26-31-13-10-9-12-29(31)23-33(46)27-48/h9-18,21-22,24-25,33,43,48H,5-8,19-20,23,26-27H2,1-4H3/t33-,52?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair