null

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(c2)C#N)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=XRZCHJPJFOWMQI-BCFGIDLVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179595 (US9126980, 40) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(c2)C#N)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C37H42N6O4S/c1-4-6-17-41(18-7-5-2)37(46)34-19-26(3)43(39-34)35-16-15-30(40-48(47)32-14-10-11-27(20-32)23-38)22-33(35)36(45)42-24-29-13-9-8-12-28(29)21-31(42)25-44/h8-16,19-20,22,31,40,44H,4-7,17-18,21,24-25H2,1-3H3/t31-,48?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	562	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179595 (US9126980, 40) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc(c2)C#N)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C37H42N6O4S/c1-4-6-17-41(18-7-5-2)37(46)34-19-26(3)43(39-34)35-16-15-30(40-48(47)32-14-10-11-27(20-32)23-38)22-33(35)36(45)42-24-29-13-9-8-12-28(29)21-31(42)25-44/h8-16,19-20,22,31,40,44H,4-7,17-18,21,24-25H2,1-3H3/t31-,48?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	673	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair