null

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)-c2cnco2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=AEKOLQMXIKYYOD-IIISYTOMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179599 (US9126980, 44) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)-c2cnco2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C39H44N6O5S/c1-4-6-18-43(19-7-5-2)39(48)35-20-27(3)45(41-35)36-17-14-31(42-51(49)33-15-12-28(13-16-33)37-23-40-26-50-37)22-34(36)38(47)44-24-30-11-9-8-10-29(30)21-32(44)25-46/h8-17,20,22-23,26,32,42,46H,4-7,18-19,21,24-25H2,1-3H3/t32-,51?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	522	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179599 (US9126980, 44) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)-c2cnco2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C39H44N6O5S/c1-4-6-18-43(19-7-5-2)39(48)35-20-27(3)45(41-35)36-17-14-31(42-51(49)33-15-12-28(13-16-33)37-23-40-26-50-37)22-34(36)38(47)44-24-30-11-9-8-10-29(30)21-32(44)25-46/h8-17,20,22-23,26,32,42,46H,4-7,18-19,21,24-25H2,1-3H3/t32-,51?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	885	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair