BDBM179600 US9126980, 45

SMILES: CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccsc2C(=O)OC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO

InChI Key: InChIKey=BHVDWNLNZMFFPY-PVKKZCMXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179600 (US9126980, 45) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccsc2C(=O)OC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C36H43N5O6S2/c1-5-7-16-39(17-8-6-2)35(44)30-19-24(3)41(37-30)31-14-13-27(38-49(46)32-15-18-48-33(32)36(45)47-4)21-29(31)34(43)40-22-26-12-10-9-11-25(26)20-28(40)23-42/h9-15,18-19,21,28,38,42H,5-8,16-17,20,22-23H2,1-4H3/t28-,49?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179600 (US9126980, 45) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccsc2C(=O)OC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C36H43N5O6S2/c1-5-7-16-39(17-8-6-2)35(44)30-19-24(3)41(37-30)31-14-13-27(38-49(46)32-15-18-48-33(32)36(45)47-4)21-29(31)34(43)40-22-26-12-10-9-11-25(26)20-28(40)23-42/h9-15,18-19,21,28,38,42H,5-8,16-17,20,22-23H2,1-4H3/t28-,49?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair