BDBM179623 US9127001, 6a::US9598410, Compound 6a

SMILES: CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1cccc(c1)C#N

InChI Key: InChIKey=GSTJILNDTJSGOY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179623 (US9127001, 6a | US9598410, Compound 6a) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1cccc(c1)C#N Show InChI InChI=1S/C22H18F2N4O/c1-14(29)27-8-7-21-19(13-27)22(16-4-2-3-15(9-16)11-25)26-28(21)12-17-5-6-18(23)10-20(17)24/h2-6,9-10H,7-8,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179623 (US9127001, 6a | US9598410, Compound 6a) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1cccc(c1)C#N Show InChI InChI=1S/C22H18F2N4O/c1-14(29)27-8-7-21-19(13-27)22(16-4-2-3-15(9-16)11-25)26-28(21)12-17-5-6-18(23)10-20(17)24/h2-6,9-10H,7-8,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair