BDBM179657 US9127001, 6ak::US9598410, Compound 6ak

SMILES: CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1ccc(Cl)s1

InChI Key: InChIKey=FGRDUZHBCLBOIZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179657 (US9127001, 6ak | US9598410, Compound 6ak) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1ccc(Cl)s1 Show InChI InChI=1S/C19H16ClF2N3OS/c1-11(26)24-7-6-16-14(10-24)19(17-4-5-18(20)27-17)23-25(16)9-12-2-3-13(21)8-15(12)22/h2-5,8H,6-7,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179657 (US9127001, 6ak | US9598410, Compound 6ak) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1ccc(F)cc1F)-c1ccc(Cl)s1 Show InChI InChI=1S/C19H16ClF2N3OS/c1-11(26)24-7-6-16-14(10-24)19(17-4-5-18(20)27-17)23-25(16)9-12-2-3-13(21)8-15(12)22/h2-5,8H,6-7,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair