BDBM179660 US9127001, 6an::US9598410, Compound 6an

SMILES: CC(c1ccc(F)cc1)n1nc(c2CN(CCc12)C(C)=O)-c1cccc(c1)C#N

InChI Key: InChIKey=RYTBGHVRJZEDBS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179660 (US9127001, 6an | US9598410, Compound 6an) Show SMILES CC(c1ccc(F)cc1)n1nc(c2CN(CCc12)C(C)=O)-c1cccc(c1)C#N Show InChI InChI=1S/C23H21FN4O/c1-15(18-6-8-20(24)9-7-18)28-22-10-11-27(16(2)29)14-21(22)23(26-28)19-5-3-4-17(12-19)13-25/h3-9,12,15H,10-11,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179660 (US9127001, 6an | US9598410, Compound 6an) Show SMILES CC(c1ccc(F)cc1)n1nc(c2CN(CCc12)C(C)=O)-c1cccc(c1)C#N Show InChI InChI=1S/C23H21FN4O/c1-15(18-6-8-20(24)9-7-18)28-22-10-11-27(16(2)29)14-21(22)23(26-28)19-5-3-4-17(12-19)13-25/h3-9,12,15H,10-11,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair