BDBM179815 Myxochelin J10

SMILES: OC[C@H](CCCCNC(=O)c1cccc(O)c1O)NC(=O)c1ccccc1F

InChI Key: InChIKey=SYLPCECHJCHTFJ-ZDUSSCGKSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM179815 (Myxochelin J10) Show SMILES OC[C@H](CCCCNC(=O)c1cccc(O)c1O)NC(=O)c1ccccc1F |r| Show InChI InChI=1S/C20H23FN2O5/c21-16-9-2-1-7-14(16)20(28)23-13(12-24)6-3-4-11-22-19(27)15-8-5-10-17(25)18(15)26/h1-2,5,7-10,13,24-26H,3-4,6,11-12H2,(H,22,27)(H,23,28)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hans Knöll Institute					Assay Description Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...				Chembiochem 16: 2445-50 (2015) Article DOI: 10.1002/cbic.201500446 BindingDB Entry DOI: 10.7270/Q2R2105R
					More data for this Ligand-Target Pair