BDBM179977 US9669035, B-14
SMILES: CCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccc(CNCC)cc3n12
InChI Key: InChIKey=MSHIPDFLJNFAJC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat)) | BDBM179977 (US9669035, B-14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 7.8 | 25 |
JANSSEN PHARMACEUTICA NV US Patent | Assay Description Rat recombinant PDE10A (rPDE10A2) was expressed in Sf9 cells using a recombinant rPDE10A baculovirus construct. Cells were harvested after 48 h of in... | US Patent US9669035 (2017) BindingDB Entry DOI: 10.7270/Q2Z60M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human)) | BDBM179977 (US9669035, B-14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | 7.8 | 25 |
JANSSEN PHARMACEUTICA NV US Patent | Assay Description Human recombinant PDE2A (hPDE2A) was expressed in Sf9 cells using a recombinant rPDE10A baculovirus construct. Cells were harvested after 48 h of inf... | US Patent US9669035 (2017) BindingDB Entry DOI: 10.7270/Q2Z60M6H | |||||||||||
More data for this Ligand-Target Pair |