BDBM18042 N-[2-({2-amino-6-ethyl-5-[4-(3-methoxypropyl)-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl]pyrimidin-4-yl}amino)ethyl]benzamide::diaminopyrimidine renin inhibitor compound, 10

SMILES: CCc1nc(N)nc(NCCNC(=O)c2ccccc2)c1-c1ccc2OC(C)(C)C(=O)N(CCCOC)c2c1

InChI Key: InChIKey=ZIDHSCRCIUQUIX-UHFFFAOYSA-N

Data: 1 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 18042

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
BDBM18042 (N-[2-({2-amino-6-ethyl-5-[4-(3-methoxypropyl)-2,2-...)	Renin (Homo sapiens (Human))	PC cid PC sid	DrugBank GoogleScholar KEGG PDB		-8.28	-5.69	-2.59	6.02	7	28
	Pfizer				Anal Biochem 360: 30-40 (2007)