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SMILES: CC1(C)CN(CCN1)c1ccc(cc1)-c1oc(nc1C(N)=O)-c1cccc2[nH]ccc12

InChI Key: InChIKey=YFLNJIAXYKROBA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM180870 (US9133180, 11) Show SMILES CC1(C)CN(CCN1)c1ccc(cc1)-c1oc(nc1C(N)=O)-c1cccc2[nH]ccc12 Show InChI InChI=1S/C24H25N5O2/c1-24(2)14-29(13-12-27-24)16-8-6-15(7-9-16)21-20(22(25)30)28-23(31-21)18-4-3-5-19-17(18)10-11-26-19/h3-11,26-27H,12-14H2,1-2H3,(H2,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46.3	n/a	n/a	n/a	n/a	7.5	25
SAREUM LIMITED US Patent					Assay Description Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...				US Patent US9133180 (2015) BindingDB Entry DOI: 10.7270/Q2P55M9X
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM180870 (US9133180, 11) Show SMILES CC1(C)CN(CCN1)c1ccc(cc1)-c1oc(nc1C(N)=O)-c1cccc2[nH]ccc12 Show InChI InChI=1S/C24H25N5O2/c1-24(2)14-29(13-12-27-24)16-8-6-15(7-9-16)21-20(22(25)30)28-23(31-21)18-4-3-5-19-17(18)10-11-26-19/h3-11,26-27H,12-14H2,1-2H3,(H2,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.54	n/a	n/a	n/a	n/a	7.5	25
SAREUM LIMITED US Patent					Assay Description Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...				US Patent US9133180 (2015) BindingDB Entry DOI: 10.7270/Q2P55M9X
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM180870 (US9133180, 11) Show SMILES CC1(C)CN(CCN1)c1ccc(cc1)-c1oc(nc1C(N)=O)-c1cccc2[nH]ccc12 Show InChI InChI=1S/C24H25N5O2/c1-24(2)14-29(13-12-27-24)16-8-6-15(7-9-16)21-20(22(25)30)28-23(31-21)18-4-3-5-19-17(18)10-11-26-19/h3-11,26-27H,12-14H2,1-2H3,(H2,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15.2	n/a	n/a	n/a	n/a	7.5	25
SAREUM LIMITED US Patent					Assay Description Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...				US Patent US9133180 (2015) BindingDB Entry DOI: 10.7270/Q2P55M9X
					More data for this Ligand-Target Pair