BDBM181150 US9138431, R-NORKETOTIFEN (RNORK)::US9138431, RS-NORKETOTIFEN (NORK)::US9138431, RS-NORKETOTIFEN (RSNORK)::US9138431, S-NORKETOTIFEN (SNORK)::US9333199, RS-NORKETOTIFEN (NORK)
SMILES: O=[#6]-1-[#6]-c2ccccc2\[#6](-c2ccsc-12)=[#6]-1/[#6]-[#6]-[#7]-[#6]-[#6]-1
InChI Key: InChIKey=IYSYPCSSDZBWHN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H4 receptor (Homo sapiens (Human)) | BDBM181150 (US9138431, R-NORKETOTIFEN (RNORK) | US9138431, RS-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BRIDGE PHARMA, INC. US Patent | Assay Description The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine... | US Patent US9333199 (2016) BindingDB Entry DOI: 10.7270/Q2639NMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM181150 (US9138431, R-NORKETOTIFEN (RNORK) | US9138431, RS-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
BRIDGE PHARMA, INC. US Patent | Assay Description The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine... | US Patent US9333199 (2016) BindingDB Entry DOI: 10.7270/Q2639NMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H4 receptor (Homo sapiens (Human)) | BDBM181150 (US9138431, R-NORKETOTIFEN (RNORK) | US9138431, RS-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BRIDGE PHARMA, INC. US Patent | Assay Description Histamine H-4 Receptor Binding Assay | US Patent US9138431 (2015) BindingDB Entry DOI: 10.7270/Q26W98WT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM181150 (US9138431, R-NORKETOTIFEN (RNORK) | US9138431, RS-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
BRIDGE PHARMA, INC. US Patent | Assay Description Affinities of the test compounds for peripheral human histamine H-4-receptors were assessed using receptor-binding assays. The specific binding of th... | US Patent US9138431 (2015) BindingDB Entry DOI: 10.7270/Q26W98WT | |||||||||||
More data for this Ligand-Target Pair |