BDBM18211 1-(cyclopropylmethyl)-2-methyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 16c

SMILES: CC1COc2cc3[nH]c(=O)cc(c3cc2N1CC1CC1)C(F)(F)F

InChI Key: InChIKey=YAQFNSNOLMJAPU-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM18211 (1-(cyclopropylmethyl)-2-methyl-9-(trifluoromethyl)...) Show SMILES CC1COc2cc3[nH]c(=O)cc(c3cc2N1CC1CC1)C(F)(F)F Show InChI InChI=1S/C17H17F3N2O2/c1-9-8-24-15-6-13-11(4-14(15)22(9)7-10-2-3-10)12(17(18,19)20)5-16(23)21-13/h4-6,9-10H,2-3,7-8H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc.					Assay Description The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...				J Med Chem 50: 2486-96 (2007) Article DOI: 10.1021/jm061329j BindingDB Entry DOI: 10.7270/Q20R9MNK
					More data for this Ligand-Target Pair