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SMILES: FC(F)(F)c1cc(=O)[nH]c2cc3OCC4CCCCN4c3cc12

InChI Key: InChIKey=DOFXICUQEPDFKZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18222   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Homo sapiens (Human))		BDBM18222
PNG
(4-(trifluoromethyl)-1,2,7,8,9,10,10a,11-octahydro-...)
Show SMILES FC(F)(F)c1cc(=O)[nH]c2cc3OCC4CCCCN4c3cc12
Show InChI InChI=1S/C16H15F3N2O2/c17-16(18,19)11-6-15(22)20-12-7-14-13(5-10(11)12)21-4-2-1-3-9(21)8-23-14/h5-7,9H,1-4,8H2,(H,20,22)
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 16n/an/an/a 14n/an/an/an/a



Ligand Pharmaceuticals Inc.



Assay Description
The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...

J Med Chem 50: 2486-96 (2007)


Article DOI: 10.1021/jm061329j
BindingDB Entry DOI: 10.7270/Q20R9MNK
More data for this
Ligand-Target Pair