BDBM182228 US9676728, 8-B (±)-2-(1-Amino-1-(2-methoxy-4,6-dimethylphenyl)ethyl)-1H-benzo[d]imidazole-5-carbonitrile
SMILES: COc1cc(C)cc(C)c1C(C)(N)c1nc2cc(ccc2[nH]1)C#N
InChI Key:
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Complement factor B (Homo sapiens (Human)) | BDBM182228 (US9676728, 8-B (±)-2-(1-Amino-1-(2-methoxy-4,6-dim...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Novartis AG US Patent | Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi... | US Patent US9676728 (2017) BindingDB Entry DOI: 10.7270/Q2QN64W8 | |||||||||||
More data for this Ligand-Target Pair |