Found 4 hits for monomerid = 182337 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM182337
(US9145392, 38)Show SMILES CN(C)CCn1cc(nc1C1CCN(CC1)c1ncnc(N)c1C(N)=O)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C24H28F4N8O/c1-34(2)9-10-36-12-18(15-3-4-17(25)16(11-15)24(26,27)28)33-22(36)14-5-7-35(8-6-14)23-19(21(30)37)20(29)31-13-32-23/h3-4,11-14H,5-10H2,1-2H3,(H2,30,37)(H2,29,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH
US Patent
| Assay Description
A TTP Mosquito liquid handling instrument is used to place 125n1 of the appropriate concentration of inhibitor in 100% DMSO (for a dose response curv... |
US Patent US9145392 (2015)
BindingDB Entry DOI: 10.7270/Q2NZ86D2 |
More data for this
Ligand-Target Pair | |
1,3-beta-glucan synthase component GSC2
(Saccharomyces cerevisiae) | BDBM182337
(US9145392, 38)Show SMILES CN(C)CCn1cc(nc1C1CCN(CC1)c1ncnc(N)c1C(N)=O)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C24H28F4N8O/c1-34(2)9-10-36-12-18(15-3-4-17(25)16(11-15)24(26,27)28)33-22(36)14-5-7-35(8-6-14)23-19(21(30)37)20(29)31-13-32-23/h3-4,11-14H,5-10H2,1-2H3,(H2,30,37)(H2,29,31,32) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM182337
(US9145392, 38)Show SMILES CN(C)CCn1cc(nc1C1CCN(CC1)c1ncnc(N)c1C(N)=O)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C24H28F4N8O/c1-34(2)9-10-36-12-18(15-3-4-17(25)16(11-15)24(26,27)28)33-22(36)14-5-7-35(8-6-14)23-19(21(30)37)20(29)31-13-32-23/h3-4,11-14H,5-10H2,1-2H3,(H2,30,37)(H2,29,31,32) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human)) | BDBM182337
(US9145392, 38)Show SMILES CN(C)CCn1cc(nc1C1CCN(CC1)c1ncnc(N)c1C(N)=O)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C24H28F4N8O/c1-34(2)9-10-36-12-18(15-3-4-17(25)16(11-15)24(26,27)28)33-22(36)14-5-7-35(8-6-14)23-19(21(30)37)20(29)31-13-32-23/h3-4,11-14H,5-10H2,1-2H3,(H2,30,37)(H2,29,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Merck Patent GmbH
US Patent
| Assay Description
P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo... |
US Patent US9145392 (2015)
BindingDB Entry DOI: 10.7270/Q2NZ86D2 |
More data for this
Ligand-Target Pair | |
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