BDBM182725 US9145402, 32

SMILES: CNc1nc(Nc2cc(F)c(cc2OC)N2CCCCC2=O)ncc1C(F)(F)F

InChI Key: InChIKey=VQTACLUNJOFGAM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM182725 (US9145402, 32) Show SMILES CNc1nc(Nc2cc(F)c(cc2OC)N2CCCCC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H19F4N5O2/c1-23-16-10(18(20,21)22)9-24-17(26-16)25-12-7-11(19)13(8-14(12)29-2)27-6-4-3-5-15(27)28/h7-9H,3-6H2,1-2H3,(H2,23,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...				US Patent US9145402 (2015) BindingDB Entry DOI: 10.7270/Q2J67FQ3
					More data for this Ligand-Target Pair