BDBM182734 US9145408, 369

SMILES: N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1

InChI Key: InChIKey=HOWIQHYXNHBQBA-JHITZODSSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 182734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human))	BDBM182734 (US9145408, 369) Show SMILES N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1 |r,TLB:9:7:23:4.2.3,23:24:31:27.28.29,24:23:7.8.6:4.2.3| Show InChI InChI=1S/C26H34N4O3/c27-26-10-4-7-18(30(26)19-12-16-5-3-6-17(11-16)13-19)14-20(15-26)29-22-9-2-1-8-21(22)28-23(24(29)31)25(32)33/h1-2,8-9,16-20H,3-7,10-15,27H2,(H,32,33)/t16?,17?,18-,19?,20+,26+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	178	-8.55	n/a	n/a	n/a	n/a	n/a	7.4	4
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...				US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM182734 (US9145408, 369) Show SMILES N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1 |r,TLB:9:7:23:4.2.3,23:24:31:27.28.29,24:23:7.8.6:4.2.3| Show InChI InChI=1S/C26H34N4O3/c27-26-10-4-7-18(30(26)19-12-16-5-3-6-17(11-16)13-19)14-20(15-26)29-22-9-2-1-8-21(22)28-23(24(29)31)25(32)33/h1-2,8-9,16-20H,3-7,10-15,27H2,(H,32,33)/t16?,17?,18-,19?,20+,26+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.03E+3	-7.35	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN,...				US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM182734 (US9145408, 369) Show SMILES N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1 |r,TLB:9:7:23:4.2.3,23:24:31:27.28.29,24:23:7.8.6:4.2.3| Show InChI InChI=1S/C26H34N4O3/c27-26-10-4-7-18(30(26)19-12-16-5-3-6-17(11-16)13-19)14-20(15-26)29-22-9-2-1-8-21(22)28-23(24(29)31)25(32)33/h1-2,8-9,16-20H,3-7,10-15,27H2,(H,32,33)/t16?,17?,18-,19?,20+,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.35E+3	-6.68	n/a	n/a	n/a	n/a	n/a	7.4	4
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description Alpha-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned i...				US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM182734 (US9145408, 369) Show SMILES N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1 |r,TLB:9:7:23:4.2.3,23:24:31:27.28.29,24:23:7.8.6:4.2.3| Show InChI InChI=1S/C26H34N4O3/c27-26-10-4-7-18(30(26)19-12-16-5-3-6-17(11-16)13-19)14-20(15-26)29-22-9-2-1-8-21(22)28-23(24(29)31)25(32)33/h1-2,8-9,16-20H,3-7,10-15,27H2,(H,32,33)/t16?,17?,18-,19?,20+,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>2.00E+4	>-6.41	n/a	n/a	n/a	n/a	n/a	7.4	25
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description Beta-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug m...				US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3
					More data for this Ligand-Target Pair
Opioid growth factor receptor-like protein 1 (Homo sapiens (Human))	BDBM182734 (US9145408, 369) Show SMILES N[C@]12CCC[C@H](C[C@@H](C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CC2CCCC(C2)C1 |r,TLB:9:7:23:4.2.3,23:24:31:27.28.29,24:23:7.8.6:4.2.3| Show InChI InChI=1S/C26H34N4O3/c27-26-10-4-7-18(30(26)19-12-16-5-3-6-17(11-16)13-19)14-20(15-26)29-22-9-2-1-8-21(22)28-23(24(29)31)25(32)33/h1-2,8-9,16-20H,3-7,10-15,27H2,(H,32,33)/t16?,17?,18-,19?,20+,26+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	545	n/a	n/a	7.4	4
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description ORL-1 Receptor [35S]GTPγS Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (...				US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3
					More data for this Ligand-Target Pair