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SMILES: COc1cc(C)cc(C)c1C(OCC(N)=O)(c1nc2cc(ccc2[nH]1)C#N)C(F)(F)F

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182859   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Complement factor B


(Homo sapiens (Human))		BDBM182859
PNG
(US9676728, 10-C (±)-2-(1-(5-Cyano-1H-benzo[d]imida...)
Show SMILES COc1cc(C)cc(C)c1C(OCC(N)=O)(c1nc2cc(ccc2[nH]1)C#N)C(F)(F)F
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 470n/an/an/an/a7.425



Novartis AG

US Patent


Assay Description
Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav...

US Patent US9676728 (2017)


BindingDB Entry DOI: 10.7270/Q2QN64W8
More data for this
Ligand-Target Pair