BDBM183171 US9150546, I-332::US9688643, I-332::US9718790, I-0332

SMILES: CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F

InChI Key: InChIKey=HGRPNRICIGWDCD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183171 (US9150546, I-332 | US9688643, I-332 | US9718790, I...) Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C24H28ClFN4O4/c1-15(2)34-20-10-9-18(11-19(20)26)27-21-28-22(32)30(13-24(3,4)14-31)23(33)29(21)12-16-5-7-17(25)8-6-16/h5-11,15,31H,12-14H2,1-4H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183171 (US9150546, I-332 | US9688643, I-332 | US9718790, I...) Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C24H28ClFN4O4/c1-15(2)34-20-10-9-18(11-19(20)26)27-21-28-22(32)30(13-24(3,4)14-31)23(33)29(21)12-16-5-7-17(25)8-6-16/h5-11,15,31H,12-14H2,1-4H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM183171 (US9150546, I-332 | US9688643, I-332 | US9718790, I...) Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC(C)(C)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C24H28ClFN4O4/c1-15(2)34-20-10-9-18(11-19(20)26)27-21-28-22(32)30(13-24(3,4)14-31)23(33)29(21)12-16-5-7-17(25)8-6-16/h5-11,15,31H,12-14H2,1-4H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair