BDBM183190 US9150546, I-354::US9688643, I-354::US9718790, I-0354

SMILES: CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=VHGWQSUSWLECNQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183190 (US9150546, I-354 | US9688643, I-354 | US9718790, I...) Show SMILES CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H26Cl2N4O5/c1-4-34-21(31)11-12-29-23(32)28-22(27-18-9-10-20(19(26)13-18)35-15(2)3)30(24(29)33)14-16-5-7-17(25)8-6-16/h5-10,13,15H,4,11-12,14H2,1-3H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183190 (US9150546, I-354 | US9688643, I-354 | US9718790, I...) Show SMILES CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H26Cl2N4O5/c1-4-34-21(31)11-12-29-23(32)28-22(27-18-9-10-20(19(26)13-18)35-15(2)3)30(24(29)33)14-16-5-7-17(25)8-6-16/h5-10,13,15H,4,11-12,14H2,1-3H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM183190 (US9150546, I-354 | US9688643, I-354 | US9718790, I...) Show SMILES CCOC(=O)CCn1c(=O)nc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C24H26Cl2N4O5/c1-4-34-21(31)11-12-29-23(32)28-22(27-18-9-10-20(19(26)13-18)35-15(2)3)30(24(29)33)14-16-5-7-17(25)8-6-16/h5-10,13,15H,4,11-12,14H2,1-3H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair