BDBM183228 US9150546, I-398::US9688643, I-398::US9718790, I-0397

SMILES: CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(Cl)cc1

InChI Key: InChIKey=QLEUXCJJSFSQEI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183228 (US9150546, I-398 | US9688643, I-398 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClFN5O6/c1-14(2)37-20-8-7-17(9-19(20)26)28-22-29-23(35)31(11-21(34)27-18(12-32)13-33)24(36)30(22)10-15-3-5-16(25)6-4-15/h3-9,14,18,32-33H,10-13H2,1-2H3,(H,27,34)(H,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183228 (US9150546, I-398 | US9688643, I-398 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClFN5O6/c1-14(2)37-20-8-7-17(9-19(20)26)28-22-29-23(35)31(11-21(34)27-18(12-32)13-33)24(36)30(22)10-15-3-5-16(25)6-4-15/h3-9,14,18,32-33H,10-13H2,1-2H3,(H,27,34)(H,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM183228 (US9150546, I-398 | US9688643, I-398 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClFN5O6/c1-14(2)37-20-8-7-17(9-19(20)26)28-22-29-23(35)31(11-21(34)27-18(12-32)13-33)24(36)30(22)10-15-3-5-16(25)6-4-15/h3-9,14,18,32-33H,10-13H2,1-2H3,(H,27,34)(H,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair