BDBM183243 US9150546, I-414::US9688643, I-414::US9718790, I-0413

SMILES: CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(C)cc1

InChI Key: InChIKey=UEHTZRMWTIRNBJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183243 (US9150546, I-414 | US9688643, I-414 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(C)cc1 Show InChI InChI=1S/C25H30FN5O6/c1-15(2)37-21-9-8-18(10-20(21)26)28-23-29-24(35)31(12-22(34)27-19(13-32)14-33)25(36)30(23)11-17-6-4-16(3)5-7-17/h4-10,15,19,32-33H,11-14H2,1-3H3,(H,27,34)(H,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183243 (US9150546, I-414 | US9688643, I-414 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(C)cc1 Show InChI InChI=1S/C25H30FN5O6/c1-15(2)37-21-9-8-18(10-20(21)26)28-23-29-24(35)31(12-22(34)27-19(13-32)14-33)25(36)30(23)11-17-6-4-16(3)5-7-17/h4-10,15,19,32-33H,11-14H2,1-3H3,(H,27,34)(H,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM183243 (US9150546, I-414 | US9688643, I-414 | US9718790, I...) Show SMILES CC(C)Oc1ccc(cc1F)\N=c1/[nH]c(=O)n(CC(=O)NC(CO)CO)c(=O)n1Cc1ccc(C)cc1 Show InChI InChI=1S/C25H30FN5O6/c1-15(2)37-21-9-8-18(10-20(21)26)28-23-29-24(35)31(12-22(34)27-19(13-32)14-33)25(36)30(23)11-17-6-4-16(3)5-7-17/h4-10,15,19,32-33H,11-14H2,1-3H3,(H,27,34)(H,28,29,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair