BDBM183293 US9150546, I-462::US9688643, I-462::US9718790, I-0471

SMILES: CCOc1ccc(cc1C)\N=c1/[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n1Cc1ccc(Cl)cc1

InChI Key: InChIKey=JQRLNIOYJHNYAQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183293 (US9150546, I-462 | US9688643, I-462 | US9718790, I...) Show SMILES CCOc1ccc(cc1C)\N=c1/[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H29ClN4O5/c1-6-35-20-12-11-19(13-16(20)2)27-22-28-23(32)30(15-25(3,4)21(31)34-5)24(33)29(22)14-17-7-9-18(26)10-8-17/h7-13H,6,14-15H2,1-5H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183293 (US9150546, I-462 | US9688643, I-462 | US9718790, I...) Show SMILES CCOc1ccc(cc1C)\N=c1/[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H29ClN4O5/c1-6-35-20-12-11-19(13-16(20)2)27-22-28-23(32)30(15-25(3,4)21(31)34-5)24(33)29(22)14-17-7-9-18(26)10-8-17/h7-13H,6,14-15H2,1-5H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM183293 (US9150546, I-462 | US9688643, I-462 | US9718790, I...) Show SMILES CCOc1ccc(cc1C)\N=c1/[nH]c(=O)n(CC(C)(C)C(=O)OC)c(=O)n1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C25H29ClN4O5/c1-6-35-20-12-11-19(13-16(20)2)27-22-28-23(32)30(15-25(3,4)21(31)34-5)24(33)29(22)14-17-7-9-18(26)10-8-17/h7-13H,6,14-15H2,1-5H3,(H,27,28,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair