BDBM183342 US9150546, I-516::US9688643, I-516::US9718790, I-0525

SMILES: CCOC(=O)CCCn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(C)cc2)c1=O

InChI Key: InChIKey=SGZWRROGODEEEX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183342 (US9150546, I-516 | US9688643, I-516 | US9718790, I...) Show SMILES CCOC(=O)CCCn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(C)cc2)c1=O Show InChI InChI=1S/C26H31ClN4O5/c1-5-35-23(32)7-6-14-30-25(33)29-24(28-20-12-13-22(21(27)15-20)36-17(2)3)31(26(30)34)16-19-10-8-18(4)9-11-19/h8-13,15,17H,5-7,14,16H2,1-4H3,(H,28,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	37
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9150546 (2015) BindingDB Entry DOI: 10.7270/Q2416VV1
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM183342 (US9150546, I-516 | US9688643, I-516 | US9718790, I...) Show SMILES CCOC(=O)CCCn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(C)cc2)c1=O Show InChI InChI=1S/C26H31ClN4O5/c1-5-35-23(32)7-6-14-30-25(33)29-24(28-20-12-13-22(21(27)15-20)36-17(2)3)31(26(30)34)16-19-10-8-18(4)9-11-19/h8-13,15,17H,5-7,14,16H2,1-4H3,(H,28,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...				US Patent US9718790 (2017) BindingDB Entry DOI: 10.7270/Q22809KB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM183342 (US9150546, I-516 | US9688643, I-516 | US9718790, I...) Show SMILES CCOC(=O)CCCn1c(=O)[nH]\c(=N/c2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(C)cc2)c1=O Show InChI InChI=1S/C26H31ClN4O5/c1-5-35-23(32)7-6-14-30-25(33)29-24(28-20-12-13-22(21(27)15-20)36-17(2)3)31(26(30)34)16-19-10-8-18(4)9-11-19/h8-13,15,17H,5-7,14,16H2,1-4H3,(H,28,29,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...				US Patent US9688643 (2017) BindingDB Entry DOI: 10.7270/Q2M32SZ2
					More data for this Ligand-Target Pair