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SMILES: Fc1ccc(cc1)-c1cnc2c(ccnn12)-c1cccnc1

InChI Key: InChIKey=IIXVLRGPFRCYFK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM183400 (US9145419, 26) Show SMILES Fc1ccc(cc1)-c1cnc2c(ccnn12)-c1cccnc1 Show InChI InChI=1S/C17H11FN4/c18-14-5-3-12(4-6-14)16-11-20-17-15(7-9-21-22(16)17)13-2-1-8-19-10-13/h1-11H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	524	n/a	n/a	n/a	n/a	7.2	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...				US Patent US9145419 (2015) BindingDB Entry DOI: 10.7270/Q208643N
					More data for this Ligand-Target Pair