BDBM183671 US9150519, 1-60
SMILES: CCCN(C(C)C)c1cc(ncn1)C(=O)Nc1ccc(cc1C)S(N)(=O)=O
InChI Key: InChIKey=HCIFSULATOSMTD-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM183671 (US9150519, 1-60) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | 7.4 | 30 |
MERCK SERONO SA US Patent | Assay Description Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm... | US Patent US9150519 (2015) BindingDB Entry DOI: 10.7270/Q2H993ZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM183671 (US9150519, 1-60) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 51 | n/a | n/a | 7.4 | 30 |
MERCK SERONO SA US Patent | Assay Description Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm... | US Patent US9150519 (2015) BindingDB Entry DOI: 10.7270/Q2H993ZK | |||||||||||
More data for this Ligand-Target Pair |