BDBM183821 US9150526, 74
SMILES: COc1cc(C)cc(OC)c1-c1cc(Cl)cc(c1)C(CC(O)=O)c1ncc(C)s1
InChI Key: InChIKey=KGLGMYFHKYGOLC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin A (CTSA) (Homo sapiens (Human)) | BDBM183821 (US9150526, 74) | PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | 6.0 | 37 |
Sanofi US Patent | Assay Description Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h... | US Patent US9150526 (2015) BindingDB Entry DOI: 10.7270/Q2QR4VXP | |||||||||||
More data for this Ligand-Target Pair |