BDBM183939 US9150526, 202

SMILES: COc1ccc(C)cc1-c1cc(cc(c1)C(F)(F)F)C(CC(O)=O)c1nnc(C)o1

InChI Key: InChIKey=BIKTYDFBMSQETH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin A (CTSA) (Homo sapiens (Human))	BDBM183939 (US9150526, 202) Show SMILES COc1ccc(C)cc1-c1cc(cc(c1)C(F)(F)F)C(CC(O)=O)c1nnc(C)o1 Show InChI InChI=1S/C21H19F3N2O4/c1-11-4-5-18(29-3)16(6-11)13-7-14(9-15(8-13)21(22,23)24)17(10-19(27)28)20-26-25-12(2)30-20/h4-9,17H,10H2,1-3H3,(H,27,28)	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	6.0	37
Sanofi US Patent					Assay Description Recombinant human cathepsin A (residues 29-480, with a C-terminal 10-His tag; R&D Systems, #1049-SE) was proteolytically activated with recombinant h...				US Patent US9150526 (2015) BindingDB Entry DOI: 10.7270/Q2QR4VXP
					More data for this Ligand-Target Pair